作者: Nikolaus Lutz-Dettinger , Annick de Jaeger , Ilse Kerremans
DOI: 10.1016/S0031-3955(05)70336-9
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摘要: Solid organ donation is a valuable method of treating various end-stage diseases in adults and children. 73 Already the early days transplantation, shortage was recognized as major obstacle to offering this treatment patients need. 30 As survival rates improve, more indications for transplantation become evident. Because availability does not equal need, waiting lists times have increased dramatically over past decade, confronting physicians with an ever-increasing moral dilemma which developing countries long been accustomed: being able help, despite knowing how help. Although new ways tackling appropriately are sought by expanding living related non–heart-beating donors, cadaveric heart-beating always will be crucial importance source organs. The current situation, annual compared deaths people organ, presented Table 1. From 5% (Europe), 10% (United Kingdom), 19% States) (all 1998) all donors Although, earlier years, organs from young children often were transplanted because less favorable results, situation has improved markedly, 152 pediatric used adult recipients, 70,128,141,159 while even serve recipients. In adults, children, donor potential estimated much higher than number donations. main factors responsible difference nonrecognition donor, that is, brain death; refusal family; misconceptions about contraindications; problems during maintenance.