BUPIVACAINE TOXICITY IN ASSOCIATION WITH EXTRADURAL ANALGESIA FOR CAESAREAN SECTION

作者: J. THORBURN , D.D. MOIR

DOI: 10.1093/BJA/56.5.551

关键词:

摘要: Evidence of central nervous system toxicity was noted in two patients undergoing extradural analgmia for Caesarean section. There no cardiovascular depression and both recovered rapidly. The had received total doses bupivacaine plain solution 357.5 mg 356.25 mg, respectively the relationship these to clinical signs is discussed.

参考文章(7)
P. LIU, H. S. FELDMAN, B. M. COVINO, R. GIASI, B. G. COVINO, Acute Cardiovascular Toxicity of Intravenous Amide Local Anesthetics in Anesthetized Ventilated Dogs Anesthesia & Analgesia. ,vol. 61, pp. 317- 322 ,(1982) , 10.1097/00132586-198210000-00058
Rudolph H. de Jong, John D. Bonin, Deaths from local anesthetic-induced convulsions in mice. Anesthesia & Analgesia. ,vol. 59, pp. 401- 405 ,(1980) , 10.1213/00000539-198006000-00002
DANIEL C. MOORE, GALE E. THOMPSON, ROBERT D. CRAWFORD, Long-acting Local Anesthetic Drugs and Convulsions with Hypoxia and Acidosis Anesthesiology. ,vol. 56, pp. 230- 232 ,(1982) , 10.1097/00000542-198203000-00020
D. C. Moore, L. E. Mather, L. D. Bridenbaugh, G. E. Thompson, R. I. Balfour, D. F. Lysons, W. G. Horton, Bupivacaine (Marcaine®): An Evaluation of its Tissue and Systemic Toxicity in Humans Acta Anaesthesiologica Scandinavica. ,vol. 21, pp. 109- 121 ,(1977) , 10.1111/J.1399-6576.1977.TB01201.X
Geoffrey T. Tucker, Daniel C. Moore, Phillip O. Bridenbaugh, L Donald Bridenbaugh, Gale E. Thompson, Systemic Absorption of Mepivacaine in Commonly Used Regional Block Procedures Anesthesiology. ,vol. 37, pp. 277- 287 ,(1972) , 10.1097/00000542-197209000-00003
C R Babst, B N Gilling, Bupivacaine: a review. Anesthesia Progress. ,vol. 25, pp. 87- 91 ,(1978)