Human fetal ventricular cardiomyocyte, RL-14 cell line, is a promising model to study drug metabolizing enzymes and their associated arachidonic acid metabolites.

作者: Zaid H. Maayah , Osama H. Elshenawy , Hassan N. Althurwi , Ghada Abdelhamid , Ayman O.S. El-Kadi

DOI: 10.1016/J.VASCN.2014.11.005

关键词:

摘要: … Briefly, the fold change in the level of target genes between … 4 C in blocking solution containing 0.15 M sodium chloride, 3 … to permit an assessment of intraday and interday accuracy and …

参考文章(42)
Hassan N Althurwi, Mandy MY Tse, Ghada Abdelhamid, Beshay NM Zordoky, Bruce D Hammock, Ayman OS El-Kadi, Soluble epoxide hydrolase inhibitor, TUPS, protects against isoprenaline-induced cardiac hypertrophy British Journal of Pharmacology. ,vol. 168, pp. 1794- 1807 ,(2013) , 10.1111/BPH.12066
Richard J. Roman, P-450 Metabolites of Arachidonic Acid in the Control of Cardiovascular Function Physiological Reviews. ,vol. 82, pp. 131- 185 ,(2002) , 10.1152/PHYSREV.00021.2001
Hesham M. Korashy, Zaid H. Maayah, Adel R. Abd-Allah, Ayman O. S. El-Kadi, Abdulqader A. Alhaider, Camel Milk Triggers Apoptotic Signaling Pathways in Human Hepatoma HepG2 and Breast Cancer MCF7 Cell Lines through Transcriptional Mechanism BioMed Research International. ,vol. 2012, pp. 593195- 593195 ,(2012) , 10.1155/2012/593195
Sook Jeong Lee, Carol S. Landon, Stanley J. Nazian, John R. Dietz, Cytochrome P-450 metabolites in endothelin-stimulated cardiac hormone secretion American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 286, ,(2004) , 10.1152/AJPREGU.00482.2003
Fengyun Xu, John R. Falck, Paul R. Ortiz de Montellano, Deanna L. Kroetz, Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes. Journal of Pharmacology and Experimental Therapeutics. ,vol. 308, pp. 887- 895 ,(2004) , 10.1124/JPET.103.059626
Osama H. Elshenawy, Anwar Anwar-Mohamed, Ayman OS El-Kadi, None, 20-Hydroxyeicosatetraenoic acid is a potential therapeutic target in cardiovascular diseases. Current Drug Metabolism. ,vol. 14, pp. 706- 719 ,(2013) , 10.2174/1389200211314060007
Neha Sehgal, Kanhaiya Lal Kumawat, Anirban Basu, Vijayalakshmi Ravindranath, Fenofibrate Reduces Mortality and Precludes Neurological Deficits in Survivors in Murine Model of Japanese Encephalitis Viral Infection PLoS ONE. ,vol. 7, pp. e35427- ,(2012) , 10.1371/JOURNAL.PONE.0035427
Thomas Thum, Jürgen Borlak, Cytochrome P450 mono‐oxygenase gene expression and protein activity in cultures of adult cardiomyocytes of the rat British Journal of Pharmacology. ,vol. 130, pp. 1745- 1752 ,(2000) , 10.1038/SJ.BJP.0703465