The efficacy of oral anticholinergics for sympathetic overactivity in a thoracic surgery clinic

摘要: Abstract Objective Little is known of the success rates oral anticholinergics for treatment primary hyperhidrosis and facial blushing as alternatives to surgical intervention. We examine predictors with these medications. Methods A retrospective review was performed at a single institution, including all patients presenting symptoms hyperhidrosis, blushing, or both from 2004 2015. All were offered trial anticholinergics. If anticholinergic therapy not successful, surgery. Statistical analyses compare who declined surgery given those proceeded Results total 381 presented (86.6%), (2.4%), (11.0%). 230 (60.4%) after using anticholinergics, 151 (39.6%) chose Patients more likely have without (89.6% vs 82.1%; P  = .02) involving axilla, torso, scalp, groin. had higher palmar site (77.6% 61.1%;  = .01) alone in combination hyperhidrosis. Presentation greater number prior attempts independent proceeding controlling concomitant symptom type location (  = .01 Conclusions The majority sympathetic overactivity decline when included algorithm. Facial each associated choosing