A Short-Term Fasting in Neonates Induces Breathing Instability and Epigenetic Modification in the Carotid Body.

作者: Machiko Shirahata , Wan-Yee Tang , Eric W. Kostuk

DOI: 10.1007/978-3-319-18440-1_20

关键词:

摘要: The respiratory control system is not fully developed in newborn, and data suggest that adequate nutrition important for the development of system. Infants need to be fed every 2–4 h maintain appropriate energy levels, but a skip feeding can occur due social economical reasons or mild sickness infants. Here, we asked questions if short-term fasting (1) alters carotid body (CB) chemoreceptor activity integrated function system; (2) causes epigenetic modification within Mouse pups (

参考文章(17)
Min Zhang, Josef Buttigieg, Colin A. Nurse, Neurotransmitter mechanisms mediating low-glucose signalling in cocultures and fresh tissue slices of rat carotid body The Journal of Physiology. ,vol. 578, pp. 735- 750 ,(2007) , 10.1113/JPHYSIOL.2006.121871
I. Bin-Jaliah, P. D. Maskell, P. Kumar, Indirect sensing of insulin‐induced hypoglycaemia by the carotid body in the rat The Journal of Physiology. ,vol. 556, pp. 255- 266 ,(2004) , 10.1113/JPHYSIOL.2003.058321
T. Dao, R. Y. S. Cheng, M. P. Revelo, W. Mitzner, W. Y. Tang, Hydroxymethylation as a Novel Environmental Biosensor Current Environmental Health Reports. ,vol. 1, pp. 1- 10 ,(2014) , 10.1007/S40572-013-0005-5
Ricardo Pardal, José López-Barneo, Low glucose-sensing cells in the carotid body. Nature Neuroscience. ,vol. 5, pp. 197- 198 ,(2002) , 10.1038/NN812
Ramón Alvarez-Buylla, Elena R. de Alvarez-Buylla, Carotid sinus receptors participate in glucose homeostasis. Respiration Physiology. ,vol. 72, pp. 347- 359 ,(1988) , 10.1016/0034-5687(88)90093-X
Y. Koyama, R. H. Coker, E. E. Stone, D. B. Lacy, K. Jabbour, P. E. Williams, D. H. Wasserman, Evidence that carotid bodies play an important role in glucoregulation in vivo. Diabetes. ,vol. 49, pp. 1434- 1442 ,(2000) , 10.2337/DIABETES.49.9.1434
Estelle B. Gauda, Machiko Shirahata, Ariel Mason, Luis E. Pichard, Eric W. Kostuk, Raul Chavez-Valdez, Inflammation in the carotid body during development and its contribution to apnea of prematurity Respiratory Physiology & Neurobiology. ,vol. 185, pp. 120- 131 ,(2013) , 10.1016/J.RESP.2012.08.005
Francis M. Hoe, Hypoglycemia in Infants and Children Advances in Pediatrics. ,vol. 55, pp. 367- 384 ,(2008) , 10.1016/J.YAPD.2008.07.008
Alexander Balbir, Boris Lande, Robert S. Fitzgerald, Vsevolod Polotsky, Wayne Mitzner, Machiko Shirahata, Behavioral and respiratory characteristics during sleep in neonatal DBA/2J and A/J mice. Brain Research. ,vol. 1241, pp. 84- 91 ,(2008) , 10.1016/J.BRAINRES.2008.09.008
Claude Gaultier, Ha Trang, Stéphane Dauger, Jorge Gallego, Pediatric Disorders with Autonomic Dysfunction: What Role for PHOX2B? Pediatric Research. ,vol. 58, pp. 1- 6 ,(2005) , 10.1203/01.PDR.0000166755.29277.C4