Knowledge, ignorance and priorities for research in key areas of cancer survivorship: findings from a scoping review

摘要: BACKGROUND: Patients who have completed initial cancer treatment (cancer survivors) been relatively neglected. We need data to help us better understand the needs of this group and underpin evidence-based service development. METHODS: Scoping reviews research published in last two decades focussing on problems faced by survivors, effectiveness interventions for these were undertaken. The aim was identify what we know, do not know opportunities where could provide new information. searched for, retrieved rapidly appraised systematic sourced from most common electronic databases supplemented more recently individual studies. RESULTS: evidence is surprisingly limited. some knowledge prevalence nature depression, pain fatigue survivors. much less about cognitive physical impairment, employment, financial well-being relationships. Even evidence, it mostly only moderate quality, often breast focuses almost exclusively early phase survivorship. good drug treatments but other symptoms. Interventions based rehabilitative self-management approaches remain stages evaluation. INTERPRETATION: There has a substantial amount describing many experienced This strongest area symptoms period soon after treatment. However, quality poor, topics little examined. urgently natural evolution scale survivors obtained well-designed, large-scale cohort studies robust testing clinical trials. Given current financially constrained funding environment, suggest areas which strategic investment might give findings that potential make major impact patient 5-year time scale. British Journal Cancer (2011) 105, S82–S94; doi:10.1038/bjc.2011.425 www.bjcancer.com & 2011 Research UK