The role of driver sleepiness in car crashes: a systematic review of epidemiological studies.

摘要: To assess the available evidence for a causal role of driver sleepiness in car crashes or crash injury, and to quantify effect, systematic review international literature was conducted. The included all studies with fatigue-related exposure measure, injury outcome measure comparison group, regardless publication status, language date study. Eighteen cross-sectional one case-control study fulfilled inclusion criteria. exposures investigated these were sleep disorders (n = 14), shift work 2), deprivation/fragmentation 1), excessive daytime 2). Only used an measure. Studies limited their ability establish relationship by design, biases, many cases, small sample sizes. better quality suggestive positive between fatigue risk, but could not provide reliable estimates strength association. provided moderately strong association apnoea risk adjusted odds ratio 7.2 (95% confidence interval 2.4-21.8). We conclude that direct epidemiological is weak, effect. estimate burden due population, information required from well-designed observational about prevalence driving population size this confers.