Experimental evidence for the role of lipids in adherence of Candida spp. to human buccal epithelial cells.

摘要: Lipids extracted from Candida albicans and C. tropicalis, but not the weakly adherent pseudotropicalis, significantly blocked in vitro adherence of respective yeast cells to buccal epithelial cells. The percentage reduction control values ranged between 16.4 42.1%, depending on species, strain, solvent used for lipid extraction. constituent classes both acetone chloroform-methanol extracts ATCC 10231 were qualitatively quantitatively analyzed. individual isolated by preparative thin-layer chromatography then tested their effects this strain Individual phospholipids, sterols, steryl esters (between 15.5 55.7% reduction). Triacylglycerols free fatty acids showed no effect whatsoever. same results obtained when standard samples investigated.