HER2 POZİTİF METASTATİK MEME KANSERİNDE PTEN, p27 VE PI3K EKSPRESYONUNUN PREDİKTİF VE PROGNOSTİK ÖNEMİ

作者: Sadi Kerem Okutur

DOI:

关键词:

摘要:

参考文章(189)
Francisco J. Esteva, Hua Guo, Siyuan Zhang, Cesar Santa-Maria, Steven Stone, Jerry S. Lanchbury, Aysegul A. Sahin, Gabriel N. Hortobagyi, Dihua Yu, PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer. American Journal of Pathology. ,vol. 177, pp. 1647- 1656 ,(2010) , 10.2353/AJPATH.2010.090885
Richard J. Pietras, David Gallardo, P. Nancy Wongvipat, H. Julie Lee, Joseph C. Poen, Dennis J. Slamon, Monoclonal antibody to HER-2/neureceptor modulates repair of radiation-induced DNA damage and enhances radiosensitivity of human breast cancer cells overexpressing this oncogene. Cancer Research. ,vol. 59, pp. 1347- 1355 ,(1999)
F. Niculescu, H. G. Rus, R. Vlaicu, M. Retegan, Persistent complement activation on tumor cells in breast cancer American Journal of Pathology. ,vol. 140, pp. 1039- 1043 ,(1992)
Angel Alkarain, Joyce Slingerland, Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer. Breast Cancer Research. ,vol. 6, pp. 13- 21 ,(2003) , 10.1186/BCR722
David Naor, Ronit Vogt Sionov, Dvorah Ish-Shalom, CD44: Structure, Function and Association with the Malignant Process Advances in Cancer Research. ,vol. 71, pp. 241- 319 ,(1997) , 10.1016/S0065-230X(08)60101-3
Vito J. Spataro, Heather Litman, Giuseppe Viale, Fausto Maffini, Michele Masullo, Rastko Golouh, Francisco J. Martinez-Tello, Piergioranni Grigolato, Keith B. Shilkin, Barry A. Gusterson, Monica Castiglione-Gertsch, Karen Price, Jurii Lindtner, Hernan Cortés-Funes, Edda Simoncini, Michael J. Byrne, John Collins, Richard D. Gelber, Alan S. Coates, Aron Goldhirsch, Decreased immunoreactivity for p27 protein in patients with early-stage breast carcinoma is correlated with HER-2/neu overexpression and with benefit from one course of perioperative chemotherapy in patients with negative lymph node status: results from International Breast Cancer Study Group Trial V. Cancer. ,vol. 97, pp. 1591- 1600 ,(2003) , 10.1002/CNCR.11224
Charis Eng, Monica Peacocke, PTEN and inherited hamartoma-cancer syndromes Nature Genetics. ,vol. 19, pp. 223- 223 ,(1998) , 10.1038/897
Gülten Tekuzman, Esmen Baltali, Aysegül Üner, Gülnur Güler, Nilüfer Güler, Hüseyin Engin, Expression of PTEN, cyclin D1, P27/KIP1 in invasive ductal carcinomas of the breast and correlation with clinicopathological parameters Bulletin Du Cancer. ,vol. 93, pp. 10021- 10026 ,(2006)
Writing Group for the Women's Health Initiative Investigators, Writing Group for the Women's Health Initiative Investigators, None, Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial JAMA. ,vol. 288, pp. 321- 333 ,(2002) , 10.1001/JAMA.288.3.321
Steven Seelig, Carlos L. Arteaga, Walter King, F. Michael Yakes, Wichai Chinratanalab, Christoph A. Ritter, Herceptin-induced Inhibition of Phosphatidylinositol-3 Kinase and Akt Is Required for Antibody-mediated Effects on p27, Cyclin D1, and Antitumor Action Cancer Research. ,vol. 62, pp. 4132- 4141 ,(2002)