The IL-33/ST2 pathway--A new therapeutic target in cardiovascular disease.

作者: Ashley M. Miller , Foo Y. Liew

DOI: 10.1016/J.PHARMTHERA.2011.02.005

关键词:

摘要: … IL-33 are limited by a soluble decoy form of ST2 (sST2). Recent studies indicate a protective role for IL-33 … currently available data showing the role for IL-33 and its receptor ST2L within …

参考文章(79)
James L. Januzzi, W. Frank Peacock, Alan S. Maisel, Claudia U. Chae, Robert L. Jesse, Aaron L. Baggish, Michelle O’Donoghue, Rahul Sakhuja, Annabel A. Chen, Roland R.J. van Kimmenade, Kent B. Lewandrowski, Donald M. Lloyd-Jones, Alan H.B. Wu, Measurement of the Interleukin Family Member ST2 in Patients With Acute Dyspnea: Results From the PRIDE (Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department) Study Journal of the American College of Cardiology. ,vol. 50, pp. 607- 613 ,(2007) , 10.1016/J.JACC.2007.05.014
Robin A.P. Weir, Ashley M. Miller, Grace E.J. Murphy, Suzanne Clements, Tracey Steedman, John M.C. Connell, Iain B. McInnes, Henry J. Dargie, John J.V. McMurray, Serum soluble ST2: a potential novel mediator in left ventricular and infarct remodeling after acute myocardial infarction. Journal of the American College of Cardiology. ,vol. 55, pp. 243- 250 ,(2010) , 10.1016/J.JACC.2009.08.047
Quentin Espinassous, Elvira Garcia-de-Paco, Ignacio Garcia-Verdugo, Monique Synguelakis, Sonja von Aulock, Jean-Michel Sallenave, Andrew N. J. McKenzie, Jean Kanellopoulos, IL-33 Enhances Lipopolysaccharide-Induced Inflammatory Cytokine Production from Mouse Macrophages by Regulating Lipopolysaccharide Receptor Complex Journal of Immunology. ,vol. 183, pp. 1446- 1455 ,(2009) , 10.4049/JIMMUNOL.0803067
Damo Xu, Woon Ling Chan, Bernard P. Leung, Fang-ping Huang, Rachel Wheeler, David Piedrafita, John H. Robinson, Foo Y. Liew, Selective Expression of a Stable Cell Surface Molecule on Type 2 but Not Type 1 Helper T Cells Journal of Experimental Medicine. ,vol. 187, pp. 787- 794 ,(1998) , 10.1084/JEM.187.5.787
Foo Y. Liew, Nick I. Pitman, Iain B. McInnes, Disease-associated functions of IL-33: the new kid in the IL-1 family Nature Reviews Immunology. ,vol. 10, pp. 103- 110 ,(2010) , 10.1038/NRI2692
Abelardo Martinez-Rumayor, Carlos A. Camargo, Sandy M. Green, Aaron L. Baggish, Michelle O’Donoghue, James L. Januzzi, Soluble ST2 plasma concentrations predict 1-year mortality in acutely dyspneic emergency department patients with pulmonary disease. American Journal of Clinical Pathology. ,vol. 130, pp. 578- 584 ,(2008) , 10.1309/WMG2BFRC97MKKQKP
S. Ali, M. Huber, C. Kollewe, S. C. Bischoff, W. Falk, M. U. Martin, IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 18660- 18665 ,(2007) , 10.1073/PNAS.0705939104
Benjamin Dieplinger, Alfons Gegenhuber, Gerhard Kaar, Werner Poelz, Meinhard Haltmayer, Thomas Mueller, Prognostic value of established and novel biomarkers in patients with shortness of breath attending an emergency department. Clinical Biochemistry. ,vol. 43, pp. 714- 719 ,(2010) , 10.1016/J.CLINBIOCHEM.2010.02.002