Risk Factors for Dengue Virus Infection in Rural Amazonia: Population-based Cross-sectional Surveys
作者： Mônica da Silva-Nunes , Pascoal T. Muniz , Marcos S. Freire , Eliana V. P. da Silva , Rosely S. Malafronte
DOI: 10.4269/AJTMH.2008.79.485
关键词:
摘要: A comparison of dengue virus (DENV) antibody levels in paired serum samples collected from predominantly DENV-naive residents an agricultural settlement Brazilian Amazonia (baseline seroprevalence, 18.3%) showed a seroconversion rate 3.67 episodes/100 person-years at risk during 12 months follow-up. Multivariate analysis identified male sex, poverty, and migration extra-Amazonian states as significant predictors baseline DENV seropositivity, whereas history clinical diagnosis fever, travel to urban area predicted subsequent seroconversion. The laboratory surveillance acute febrile illnesses implemented the study site nearby town between 2004 2006 confirmed 11 infections among 102 episodes studied with IgM detection, reverse transcriptase-polymerase chain reaction, isolation; DENV-3 was isolated. Because exposure is associated or travel, personal protection measures when visiting high-risk areas may reduce incidence infection this rural population.
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