How do roll compaction/dry granulation affect the tableting behaviour of inorganic materials? Microhardness of ribbons and mercury porosimetry measurements of tablets.

摘要: The effect of roll compaction/dry granulation on the ribbon and tablet properties produced using different magnesium carbonates was evaluated. microhardness pore size distribution tablets were used as evaluation factors. Increasing specific compaction force resulted in higher for ribbons prepared with all four accompanied decreased part fine. Consequently, corresponding displayed a lower tensile strength. A possible correlation between particle shape, surface area resulting structure types carbonate observed. strength granules than starting materials. partial loss compactibility demand low loads during compaction. However, impact changes material depended greatly type carbonate, tableting pressure applied.