The use of preventive antibiotics in orthopaedic surgery.

摘要: The use of preventive antibiotic therapy in patients with femoral neck fractures and those treated by prosthetic joint arthroplasty is an accepted practice, yet it remains controversial other clean orthopedic surgical procedures. devastating consequences infection are the major rationale for prophylaxis. Recent data indicate that some unfavorable effects prophylaxis, such as expense drug-related side effects, can be limited restricting duration use. critical importance instituting immediately prior to surgery emphasized. authors currently favor, most clean, elective surgeries, two grams cefazolin administered intravenously one gram every eight hours 24 after surgery. This view reinforced comparing incidence 1341 total arthroplasties (0.6% rate) receiving three days prophylaxis 450 cases day Patients joints should instructed regarding possibility late infections encouraged take various further urged notify their orthopedist event any significant infectious process present.