The regulation of signaling in hematopoietic stem cell maintenance

Eri Iwai-Kanai, Hua Yuan, Chengqun Huang, M. Richard Sayen, Cynthia N. Perry-Garza, Lucy Kim, Roberta A. Gottlieb, A method to measure cardiac autophagic flux in vivo Autophagy. ,vol. 4, pp. 322- 329 ,(2008) , 10.4161/AUTO.5603

Masaaki Komatsu, Satoshi Waguri, Tomoki Chiba, Shigeo Murata, Jun-ichi Iwata, Isei Tanida, Takashi Ueno, Masato Koike, Yasuo Uchiyama, Eiki Kominami, Keiji Tanaka, Loss of autophagy in the central nervous system causes neurodegeneration in mice Nature. ,vol. 441, pp. 880- 884 ,(2006) , 10.1038/NATURE04723

Akiko Kuma, Makoto Matsui, Noboru Mizushima, LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization. Autophagy. ,vol. 3, pp. 323- 328 ,(2007) , 10.4161/AUTO.4012

Janakiraman Krishnamurthy, Matthew R. Ramsey, Keith L. Ligon, Chad Torrice, Angela Koh, Susan Bonner-Weir, Norman E. Sharpless, p16INK4a induces an age-dependent decline in islet regenerative potential. Nature. ,vol. 443, pp. 453- 457 ,(2006) , 10.1038/NATURE05092

David A. Guertin, Deanna M. Stevens, Maki Saitoh, Stephanie Kinkel, Katherine Crosby, Joon-Ho Sheen, David J. Mullholland, Mark A. Magnuson, Hong Wu, David M. Sabatini, mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice Cancer Cell. ,vol. 15, pp. 148- 159 ,(2009) , 10.1016/J.CCR.2008.12.017

Anna V Molofsky, Shalom G Slutsky, Nancy M Joseph, Shenghui He, Ricardo Pardal, Janakiraman Krishnamurthy, Norman E Sharpless, Sean J Morrison, None, Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing Nature. ,vol. 443, pp. 448- 452 ,(2006) , 10.1038/NATURE05091

Miranda Buitenhuis, Liesbeth P. Verhagen, Hanneke W. M. van Deutekom, Anders Castor, Sandra Verploegen, Leo Koenderman, Sten-Eirik W. Jacobsen, Paul J. Coffer, Protein kinase B (c-akt) regulates hematopoietic lineage choice decisions during myelopoiesis. Blood. ,vol. 111, pp. 112- 121 ,(2008) , 10.1182/BLOOD-2006-07-037572

Teruhisa Kawamura, Jotaro Suzuki, Yunyuan V Wang, Sergio Menendez, Laura Batlle Morera, Angel Raya, Geoffrey M Wahl, Juan Carlos Izpisúa Belmonte, None, Linking the p53 tumour suppressor pathway to somatic cell reprogramming Nature. ,vol. 460, pp. 1140- 1144 ,(2009) , 10.1038/NATURE08311

Akira Suzuki, Manae Tsukio Yamaguchi, Toshiaki Ohteki, Takehiko Sasaki, Tsuneyasu Kaisho, Yuki Kimura, Ritsuko Yoshida, Andrew Wakeham, Tetsuya Higuchi, Manabu Fukumoto, Takeshi Tsubata, Pamela S Ohashi, Shigeo Koyasu, Josef M Penninger, Toru Nakano, Tak W Mak, T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance Immunity. ,vol. 14, pp. 523- 534 ,(2001) , 10.1016/S1074-7613(01)00134-0

Keisuke Ito, Rosa Bernardi, Alessandro Morotti, Sahoko Matsuoka, Giuseppe Saglio, Yasuo Ikeda, Jacalyn Rosenblatt, David E. Avigan, Julie Teruya-Feldstein, Pier Paolo Pandolfi, PML targeting eradicates quiescent leukaemia-initiating cells. Nature. ,vol. 453, pp. 1072- 1078 ,(2008) , 10.1038/NATURE07016