Net costs from three perspectives of using low versus high osmolality contrast medium in diagnostic angiocardiography

摘要: Abstract Objectives . We conducted an economic analysis to assess the extent which a reduction in adverse drug reactions induced by low osmolality compared with high contrast media during diagnostic angiocardiography would result savings hospitals, society and third-party payers that offset substantially higher price of medium. Background Substitution for approximately 1 million angiocardiographic procedures performed each year United States could increase health care costs. Costeffectiveness estimates should include might occur through reduced costs managing reactions. Methods In randomized clinical trial 505 persons undergoing angiography either or medium, we measured 1) material media, 2) from three perspectives incremental resources used manage contrast-related also sensitivity analyses examine effect different assumptions regard relative risk, absolute risk on net cost use media. Results One-hundred thirty-seven (54.2%) 253 patients receiving medium 44 (17.5%) 252 experienced The average (from society's perspective) per patient was significantly (p = 0.0001) greater (mean $249) verus $92) Differential hospital's were $67 Charges professional fees payer's $182 $312) than $130) 0.42, NS). differential 33% 75%, respectively, $207 difference mean costs, but these are sensitive infrequent cases. Conclusions Although is not cost-saving angiocardiography, its partially lower management hospital may be realized payers. These methods results useful establishing payment guidelines alternative angiocardiography.