The antidiabetic activity of the herbal preparation ADD-199 in mice: a comparative study with two oral hypoglycaemic drugs
作者： L.K.N. Okine , A.K. Nyarko , N. Osei-Kwabena , I.V. Oppong , F. Barnes
DOI: 10.1016/J.JEP.2004.09.048
关键词:
摘要: Abstract The antidiabetic and antioxidant effects of the herbal preparation ADD-199 were investigated in STZ-induced diabetic C 3 H mice results compared with two allopathic hypoglycaemic drugs, glibenclamide metformin. Plasma glucose, insulin lipids as well liver glycogen, lipid peroxidation measured following treatment for 8 weeks. indicated that plasma levels normal controls at termination about 76 μmol/L to trace untreated mice. Glibenclamide increased up 70% non-diabetic whilst metformin had no effect. Basal glucose (18.8 mM) reduced 14.0 mM by 100 mg/kg
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