Design and characterization of an improved protein tyrosine phosphatase substrate-trapping mutant.

作者: Laiping Xie , Yan-Ling Zhang , Zhong-Yin Zhang

DOI: 10.1021/BI015904R

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摘要: … an improved PTP1B substrate-trapping mutant (D181A/Q262A) … It is possible that the affinity of the existing trapping mutants … to create a mutant PTPase with enhanced substrate trapping …

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