E. coli Infection Modulates the Pharmacokinetics of Oral Enrofloxacin by Targeting P-Glycoprotein in Small Intestine and CYP450 3A in Liver and Kidney of Broilers
作者： Mengjie Guo , Yong Sun , Yu Zhang , Shamsuddin Bughio , Xiaohua Dai
DOI: 10.1371/JOURNAL.PONE.0087781
关键词:
摘要: … orally administered enrofloxacin was … enrofloxacin, significantly decreased C max (0.34 vs 0.98 µg mL −1 , P = 0.000) and AUC 0-12h (4.37 vs 8.88 µg mL −1 h, P = 0.042) of enrofloxacin…
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