作者: Ranjith B. Adhikari , Indika B. Gawarammana , D.D.N. De Silva , Ashoka Dangolla , Chandima Mallawa
DOI: 10.1016/J.TOXREP.2019.08.006
关键词:
摘要: Abstract Introduction Russell’s viper envenoming in dogs is a significant problem Sri Lanka. The current study focused on investigating clinical profile, laboratory findings of three selected tests and to develop treatment strategy with Indian polyvalent Anti-Venom Serum (AVS). It was also intended report adverse effects complications caused by both Russell's venom (RVV) AVS Viper (RV) envenomed dogs. Objective To evaluate the manifestations, find out minimum effective vials record induced reactions RV Materials methods A prospective conducted bitten (n = 65) admitted Veterinary Teaching Hospital (VTH) used treat all number that administered patient decided upon second degree polynomial model X axis verses Prothrombine Time (PT), Activated Partial Thromboplastine (aPTT) Clotting (CT) Y respectively. Results Varying degrees pain were exhibited victim Mild swelling necrosis at site bite seen 54% (n = 35) 37% (n = 24) Prolonged values of, PT, aPTT CT from mean leukocyte count these 39.79 × 103/μL (normal range; 4–20 × 103/μL) (IQR:29.05 × 103/μL-45.92 × 103/μL). Statistical analysis showed initial 7 would be required vials. Therefore, range 6–15 total 7.6% (n = 5) dogs, results became normal 6 32–97 minutes. Acute Renal Failure (ARF) detected 29% (n = 19) as complication. Conclusions Systemic signs haemorrhagic lesions, cardio respiratory toxicities common Initially must administered. reported commonly. found lethal