Toxicological Evaluation of Realistic Emission Source Aerosols (TERESA)—Power plant studies: assessment of breathing pattern
作者： Edgar A. Diaz , Miriam Lemos , Brent Coull , Mark S. Long , Annette C. Rohr
DOI: 10.3109/08958378.2010.578169
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摘要: Our approach to study multi-pollutant aerosols isolates a single emissions source, evaluates the toxicity of primary and secondary particles derived from this simulates chemical reactions that occur in atmosphere after emission. Three U.S. coal-fired power plants utilizing different coals with emission controls were evaluated. Secondary organic aerosol (SOA) α-pinene and/or ammonia was added some experiments. Male Sprague-Dawley rats exposed for 6 h filtered air or atmospheric mixtures. Scenarios studied at each plant included following: (P); (oxidized) (PO); oxidized + SOA (POS); neutralized (PONS); additional control scenarios also studied. Continuous respiratory data obtained during exposures using whole body plethysmography chambers. Of 12 outcomes assessed, had statistically significant changes o...
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