The Swedish Childhood Diabetes Study--a multivariate analysis of risk determinants for diabetes in different age groups.

摘要: In a nationwide incident case-referent study stepwise univariate analysis has revealed several risk determinants for childhood diabetes mellitus. multivariate we have determined the set of that would independently predict Type 1 (insulin-dependent) diabetes. Possible interactions between and differences in profiles with different ages at onset were also examined. Reported familial insulin-treated non-insulin-treated significant factors all age groups, as was low frequency milk intake. The infections high intake foods rich nitrosamine tended to interact (OR 11.8, p=0.053) indicating synergistic effect. A Cox regression stressful life events during last year only variable affect (p=0.055). This indicated psychological stress may rather precipitate than induce short breast-feeding duration (OR=3.81), an increased body height (OR=3.82) contributed significantly predictive model youngest group (0–4 years). An preceding (OR=2.15) no vaccination against measles (OR=3.33) 5–9 years. Various nutrients had impacts on developing groups. It is concluded genetically susceptible child, which are associated eating habits, infections, status, growth pattern severe each other. varies onset. nitrosamine-rich food seem effect childhood.