Severity and age of rotavirus diarrhea, but not socioeconomic conditions, are associated with rotavirus seasonality in Venezuela.

摘要: Rotavirus (RV) epidemiology presents differences between developing and developed countries among which are seasonality age at first infection variability of strain in circulation severity disease. Since Venezuela we have distinct seasonal patterns RV occurrence examined the epidemiological profile disease associated to these by analyzing data from previous studies conducted Venezuela. Data were collected children <5 years with diarrhea seen six hospitals located five cities. Socio-demographic clinical characteristics illness analyzed according identification ELISA assay (marked versus minimal seasonality). A total 6742 episodes (1820 rotavirus positive 4922 negative) evaluated: 1951 Caracas Cumana Pto. Ordaz (minimal seasonality) 4791 Merida Valencia Mean (months) was 8.14 +/- 6.74 12.21 9.62 (P < 0.0001) areas marked respectively. more frequent (33% vs. 24%; OR = 1.536; 95% CI: 1.36-1.73) severe (dehydration: 64% 29%; 4.436; 3.61-5.44) common infants than older (79% 60%; 2.521; 2.01-3.14) cities those seasonality. Socioeconomic conditions not In environments infected younger ages is regardless malnutrition poverty. Copyright 2009 Wiley-Liss Inc.