Interstitial Fluid and Transcapillary Fluid Balance in the Lung

摘要: Alterations in extravascular lung water content when capillary pressure or plasma colloid osmotic is increased have been evaluated isolated, continuously weighed, plasma-perfused pairs of rabbit lungs. After modest increases left atrial pressure, most preparations rapidly reached a new stable weight, and thus transcapillary fluid balance, but no significant increase could be detected. In where there was still steady, slow gain weight some transvascular filtration 15 min after the moderate It concluded that only very small shifts occur lungs changes, as long this change kept below level causes oedema. This limitation pressure-induced explained by existence, close to capillaries, interstitial space containing with high protein concentration. exerted would then contribute markedly towards continuous readjustment balance lung. Experiments other workers indicate alveolar can affect isolated perfused