Melanocytic precursors of cutaneous melanoma. Estimated risks and guidelines for management.

摘要: There are several recognizable melanocytic precursors of cutaneous melanoma. These include lentigo maligna, dysplastic nevi, congenital nevi (of any size), and darkly pigmented lesions acral surfaces mucous membranes. Lentigo maligna is an uncommon dysplasia, present in 3 per 1000 individuals over the age 50 years accounting for 4 percent all melanomas. Dysplastic 2 cent white adults, may account at least a fifth cases Congenital nevomelanocytic 1 newborns; vast majority smaller than to cm diameter, while very large 20,000 500,000 newborns. Very less 0.1 melanomas, whereas small varieties 15 If with live long enough, possibly third half said develop This figure be biased high. Persons familial melanoma setting have estimated lifetime risk developing approaching 100 cent. other settings 18 size 5 Early recognition these precursor tumors, particularly high-risk (i.e., those personal or family history melanoma), careful photographic follow-up prophylactic excision most effective means reducing morbidity mortality The impact routine screening presumed unknown. Clinical judgment required balance theoretical associated given known risks surgery anesthesia individual. It must kept mind that acquired adults harmless. Probably even will remain unchanged throughout life. simple existence heighten suspicion raise awareness earliest signs malignant change.(ABSTRACT TRUNCATED AT 400 WORDS)