Cancer Chemopreventive Activity of Monoterpenes and Other Isoprenoids
作者： Pamela L. Crowell , Michael N. Gould
DOI: 10.1007/978-1-59259-767-3_25
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摘要: d-Limonene and perillyl alcohol monoterpenes with low toxicity have cancer-chemopreventive chemotherapeutic activity against solid cancers leukemias, which include most of the leading causes cancer-related death. Monoterpenes are among numerous diverse naturally occurring isoprenoids that synthesized in plants (1). Isoprenoids (10 carbons), sesquiterpenes (15 diterpenes (20 triterpenes (30 carbons). The monoterpene geraniol sesquiterpene farnesol show promise as more potent compounds than d-limonene or vivo, development for clinical cancer prevention. Although many reviews summarized anticancer activities (2-9), this chapter focuses on isoprenoid mechanisms action applications d-limonene, alcohol, geraniol, (Fig. 1).
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