Statistics for Testing Gene–Environment Interaction

作者: Momiao Xiong , Xuesen Wu

DOI: 10.1007/978-1-4419-6752-7_3

关键词:

摘要: This chapter introduces a number of new gene–environment interaction measures and develop novel statistics that are based on these measures. These simple, less computationally intensive easy to implement. It is hoped developments may open avenue for large-scale genome-wide analysis, deciphering the genetic physiological meaning interactions developing sophisticated statistical methods unraveling gene–gene leading development human cancers.

参考文章(70)
David C. Christiani, Sally W. Thurston, John C. Wain, Li Lian Xu, Li Su, Thomas J. Lynch, Geoffrey Liu, David P. Miller, Wei Zhou, Gene-Environment Interaction for the ERCC2 Polymorphisms and Cumulative Cigarette Smoking Exposure in Lung Cancer Cancer Research. ,vol. 62, pp. 1377- 1381 ,(2002)
KENNETH J. ROTHMAN, SANDER GREENLAND, ALEXANDER M. WALKER, Concepts of interaction. American Journal of Epidemiology. ,vol. 112, pp. 467- 470 ,(1980) , 10.1093/OXFORDJOURNALS.AJE.A113015
Christopher I Amos, Xifeng Wu, Peter Broderick, Ivan P Gorlov, Jian Gu, Timothy Eisen, Qiong Dong, Qing Zhang, Xiangjun Gu, Jayaram Vijayakrishnan, Kate Sullivan, Athena Matakidou, Yufei Wang, Gordon Mills, Kimberly Doheny, Ya-Yu Tsai, Wei Vivien Chen, Sanjay Shete, Margaret R Spitz, Richard S Houlston, Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1 Nature Genetics. ,vol. 40, pp. 616- 622 ,(2008) , 10.1038/NG.109
Yoshio Hiasa, Masato Ohshima, Yoshiteru Kitahori, Takashi Yuasa, Toyohisa Fujita, Chikayoshi Iwata, Promoting effects of 3-amino-1,2,4-triazole on the development of thyroid tumors in rats treated with N-bis(2-hydroxypropyl)nitrosamine. Carcinogenesis. ,vol. 3, pp. 381- 384 ,(1982) , 10.1093/CARCIN/3.4.381
P. L. F. Johnson, M. Slatkin, Accounting for Bias from Sequencing Error in Population Genetic Estimates Molecular Biology and Evolution. ,vol. 25, pp. 199- 206 ,(2007) , 10.1093/MOLBEV/MSM239
Suzanne P Linn-Rasker, AHM Van Der Helm-Van Mil, Floris A Van Gaalen, Margreet Kloppenburg, RRP De Vries, Saskia le Cessie, Ferdinand C Breedveld, Rene EM Toes, Tom WJ Huizinga, Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles Annals of the Rheumatic Diseases. ,vol. 65, pp. 366- 371 ,(2006) , 10.1136/ARD.2005.041079
Jonathan Marchini, Peter Donnelly, Lon R Cardon, None, Genome-wide strategies for detecting multiple loci that influence complex diseases Nature Genetics. ,vol. 37, pp. 413- 417 ,(2005) , 10.1038/NG1537
Joanne S. Colt, Nathaniel Rothman, Richard K. Severson, Patricia Hartge, James R. Cerhan, Nilanjan Chatterjee, Wendy Cozen, Lindsay M. Morton, Anneclaire J. De Roos, Scott Davis, Stephen Chanock, Sophia S. Wang, Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma Blood. ,vol. 113, pp. 1899- 1905 ,(2009) , 10.1182/BLOOD-2008-04-153858
Munindra Ruwali Munindra Ruwali, AJ Khan, PP Shah, AP Singh, MC Pant, Devendra Parmar Devendra Parmar, Cytochrome P450 2E1 and head and neck cancer: interaction with genetic and environmental risk factors. Environmental and Molecular Mutagenesis. ,vol. 50, pp. 473- 482 ,(2009) , 10.1002/EM.20488
Nilanjan Chatterjee, Zeynep Kalaylioglu, Roxana Moslehi, Ulrike Peters, Sholom Wacholder, Powerful Multilocus Tests of Genetic Association in the Presence of Gene-Gene and Gene-Environment Interactions American Journal of Human Genetics. ,vol. 79, pp. 1002- 1016 ,(2006) , 10.1086/509704