Lactobacillus plantarum No. 14株の抗アレルギー効果
作者： Yuko Nagata , Yuya Kamimura , Tomohide Saka , Mutsuko Yoshida , Masataka Saito
DOI: 10.3136/NSKKK.55.625
关键词:
摘要: Lactobacillus plantarum No. 14株を被験者28人に二重盲検法により摂取させ，そのスギ花粉症に対する効果を調べた．実施期間は2005年1～3月とし，No. 14株の凍結乾燥菌体を1日2.0×1010CFU, 3週間連続摂取させた．その結果，血液成分において群間に有意な差はなかったが，No. 14株摂取により総IgEの有意な減少が見られた．また摂取を終了した後でも総IgE, 好酸球数の上昇を抑制した．アレルギー症状に関しては鼻回数が摂取3週間目と後観察1週目で試験群がプラセボ群に対して有意に少なくなった．また，体脂肪率が摂取前後でプラセボ群は有意に上昇したのに対し，試験群は有意に減少した．このことからNo. 14株の摂取により花粉症が抑制され，体脂肪率が低減する可能性が示唆された．
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