Blood concentration of mepivacaine and lidocaine in mother and baby after epidural anesthesia

作者: Aron O. Lurie , Jess B. Weiss

DOI: 10.1016/0002-9378(70)90478-3

关键词:

摘要: Abstract The concentration of mepivacaine and lidocaine in mother neonate was assayed by means gas liquid chromatography. There a rapid appearance the drug maternal circulation, mean peak being attained within 5 minutes. In 19 cases anesthesia blood 2.2 μg per milliliter, whereas 1.6 milliliter. 13 milliliter 1.55 Three neonates required resuscitation these duration greater than 6 hours with total dosage anesthetic agent 600 mg. mothers showed no side effects attributable to agents.

参考文章(15)
Bernard B. Brodie, Sidney Udenfriend, THE ESTIMATION OF BASIC ORGANIC COMPOUNDS AND A TECHNIQUE FOR THE APPRAISAL OF SPECIFICITY APPLICATION TO THE CINCHONA ALKALOIDS Journal of Biological Chemistry. ,vol. 158, pp. 705- 714 ,(1945) , 10.1016/S0021-9258(19)51347-3
Mieczyslaw Finster, Paul J. Poppers, John C. Sinclair, Hisayo O. Morishima, Salha S. Daniel, ACCIDENTAL INTOXICATION OF THE FETUS WITH LOCAL ANESTHETIC DRUG DURING CAUDAL ANESTHESIA. American Journal of Obstetrics and Gynecology. ,vol. 92, pp. 922- 924 ,(1965) , 10.1016/0002-9378(65)90725-8
A. O. Lurie, C. A. Villee, A Device for the Injection of Dry Samples Prepared for Gas Liquid Chromatography Journal of Chromatographic Science. ,vol. 4, pp. 160- 161 ,(1966) , 10.1093/CHROMSCI/4.4.160
Jonathan B. Rosefsky, Mel E. Petersiel, Perinatal Deaths Associated with Mepivacaine Paracervical-Block Anesthesia in Labor New England Journal of Medicine. ,vol. 278, pp. 530- 533 ,(1968) , 10.1056/NEJM196803072781003
Hisayo O. Morishima, Salha S. Daniel, Mieczyslaw Finster, Paul J. Poppers, L Stanley James, Transmission of Mepivacaine Hydrochloride (Carbocaine) Across the Human Placenta Anesthesiology. ,vol. 27, pp. 147- 154 ,(1966) , 10.1097/00000542-196603000-00006
D. P. Braid, D. B. Scott, Effect of adrenaline on the systemic absorption of local anaesthetic drugs. Acta Anaesthesiologica Scandinavica. ,vol. 10, pp. 334- 346 ,(1966) , 10.1111/J.1399-6576.1966.TB01031.X