Neurological Involvement in COVID-19 Patients: A Narrative Review

摘要: Background Coronavirus disease 2019 (COVID-19) is a viral caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belonging to the family. The primary target of SARS-CoV-2 peripheral mucosal cells tract. Recent days have seen few cases where virus has affected extrapulmonary organ such as nervous system. Materials and Methods The present study was narrative review done using techniques systemic review, that is, Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) guidelines. Electronic databases PubMed (Medline) Google Scholar were searched systematically published article from December 1, June 5, 2020. A total 189 articles initially selected authors. final list 17 prepared following information extracted studies: design, main result, limitations study. Results Majority these descriptive studies describing spectrum signs symptoms among admitted patients. In majority studies, patients developed suggestive neurological involvement. Most common central system reported headache, followed dizziness confusion. Similarly, most involvement loss taste smell. Conclusion The concludes there are enough evidences prove infection affects both Various mechanisms proposed explain pathophysiology manifestations in COVID-19-positive needs be established verified.