Risk factors for in utero and intrapartum transmission of HIV.
作者： Laurence S. Magder , Lynne Mofenson , Mary E. Paul , Carmen D. Zorrilla , William A. Blattner
DOI: 10.1097/00126334-200501010-00016
关键词:
摘要: Objective: To identify predictors of in utero and intrapartum HIV-1 transmission infants born the Women Infants Transmission Study between 1990 2000. Methods: In infection was defined as an infant with first positive peripheral blood mononuclear cell culture and/or DNA polymerase chain reaction assay at 7 days age or younger; having a negative HIV-I younger after age. Results: Of 1709 first-born singleton children status, 166 (9.7%) were found to be infected; decreased from 18.1% 1990-1992 1.6% 1999-2000. Presumed observed 34% infected children, presumed infection, 66%. Among proportion increased over time 27% 80% (4 5) 1999-2000 (P = 0.072). Maternal antenatal viral load antiretroviral therapy associated risk both transmission. Controlling for maternal therapy, low birth weight significantly transmission, while age, CD4 + percentage, year, weight, duration membrane rupture Conclusion: Although there have been significant declines perinatal time, has increase infections transmitted utero.
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sci-hub.se 参考文章(36)
Improved birth outcomes among HIV-infected women with enhanced medicaid prenatal care American Journal of Public Health. ,vol. 90, pp. 85- 91 ,(2000) , 10.2105/AJPH.90.1.85
Pardi G, Newell Ml, Dunn Dt, Semprini Ae, Peckham Cs, Vertical transmission of HIV-1: maternal immune status and obstetric factors. The European Collaborative Study. AIDS. ,vol. 10, pp. 1675- 1681 ,(1996)
Proposed definitions for in utero versus intrapartum transmission of HIV-1. The New England Journal of Medicine. ,vol. 327, pp. 1246- 1247 ,(1992) , 10.1056/NEJM199210223271718
Elaine J Abrams, Pamela B Matheson, Pauline A Thomas, Donald M Thea, Keith Krasinski, Genevieve Lambert, Nathan Shaffer, Mahrukh Bamji, David Hutson, Katherine Grimm, Aditya Kaul, David Bateman, Martha Rogers, New York City Perinatal HIV Transmission Collaborative Study Group, Neonatal Predictors of Infection Status and Early Death Among 332 Infants at Risk of HIV-1 Infection Monitored Prospectively From Birth Pediatrics. ,vol. 96, pp. 451- 458 ,(1995)
Patricia M. Garcia, Leslie A. Kalish, Jane Pitt, Howard Minkoff, Thomas C. Quinn, Sandra K. Burchett, Janet Kornegay, Brooks Jackson, John Moye, Celine Hanson, Carmen Zorrilla, Judy F. Lew, Maternal levels of plasma human immunodeficiency virus type 1 RNA and the risk of perinatal transmission The New England Journal of Medicine. ,vol. 341, pp. 394- 402 ,(1999) , 10.1056/NEJM199908053410602
MARC BULTERYS, ANN CHAO, SOSTHÉNE MUNYEMANA, JEAN-BAPTISTE KURAWIGE, PAULA NAWROCKI, PHOCAS HABIMANA, MARTIN KAGERUKA, SPÉCIOSE MUKANTABANA, ETIENNE MBARUTSO, ABEL DUSHIMIMANA, ALFRED SAAH, Maternal human immunodeficiency virus 1 infection and intrauterine growth: a prospective cohort study in Butare, Rwanda. Pediatric Infectious Disease Journal. ,vol. 13, pp. 94- 100 ,(1994) , 10.1097/00006454-199402000-00003
M.L. Newell, D. Dunn, C.S. Peckham, A.E. Ades, G. Pardi, A.E. Semprini, C. Giaquinto, D. Truscia, A. De Rossi, L. Chieco-Bianchi, F. Zachello, I. Grosch-Worner, M. Vocks-Hauck, M. Langhof, J. Mok, F. Omenaca Teres, I. Bates, M.C. Garcia-Rodrigues, C. Canosa, Risk factors for mother-to-child transmission of HIV-1 International Journal of Gynecology & Obstetrics. ,vol. 39, pp. 357- 357 ,(1992) , 10.1016/0020-7292(92)90272-K
Wafaie Fawzi, Gernard Msamanga, Boris Renjifo, Donna Spiegelman, Ernest Urassa, Lobat Hashemi, Gretchen Antelman, Max Essex, David Hunter, Predictors of intrauterine and intrapartum transmission of HIV-1 among Tanzanian women. AIDS. ,vol. 15, pp. 1157- 1165 ,(2001) , 10.1097/00002030-200106150-00011
Louise Kuhn, Elaine J. Abrams, Pamela B. Matheson, Pauline A. Thomas, Genevieve Lambert, Mahrukh Bamji, Barbara Greenberg, Richard W. Steketee, Donald M. Thea, Timing of maternal-infant HIV transmission : associations between intrapartum factors and early polymerase chain reaction results AIDS. ,vol. 11, pp. 429- 435 ,(1997) , 10.1097/00002030-199704000-00005
Jeannette R. Ickovics, Kathleen A. Ethier, Linda J. Koenig, Tracey E. Wilson, Emmanuel B. Walter, M. Isabel Fernandez, Infant birth weight among women with or at high risk for HIV infection: the impact of clinical, behavioral, psychosocial, and demographic factors. Health Psychology. ,vol. 19, pp. 515- 523 ,(2000) , 10.1037/0278-6133.19.6.515