SPASMOLYTIC, BRONCHODILATOR AND VASORELAXANT ACTIVITY OF METHANOLIC EXTRACT OF TEPHROSIA PURPUREA
作者： Khalid Hussain Janbaz , Asma Jan , M Imran Qadir , Anwarul Hassan Gilani , None
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摘要: The methanolic extract of the whole plant Tephrosia pupurea, Linn. was subjected to find out its possible therapeutic utility validate folkloric use in native systems medicine. on application spontaneous contractions isolated rabbit jejunum preparations exerted a concentration dependent (0.003-3.0 mg/mL) relaxant effect. also caused relaxation K+(80 mM)-induced spastic contractions. These findings were further supported by observations that right ward shift Ca2+ response curves manner similar verapamil. exhibited effect carbachol and high K+ (80 tracheal observed non-specific bronchodilator is possibly mediated through channel blockade. Moreover, dose phenylephrine (1 microM) On basis above-mentioned findings, it can be concluded purpurea, gastrointestinal spasm, asthma hypertension likely calcium blockage.
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