Commensal bacteria as signal mediators within a mammalian host

作者: Franklin Faping Duan , John C. March

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摘要: Genetically engineered cells and microorganisms are provided for preventing or ameliorating diseases through genetically quorum signaling. Therapeutic methods using the to prevent ameliorate also provided. The can be express a signal used interrupt signaling-dependent virulence of an invading pathogen. provide signal-dependent expression desirable gene in order interrupt, prevent, and/or disease mammals, such as parasitic diseases, infectious autoimmune genetic disorders.

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