Use of microorganisms for reducing the level of trimethylamine in a human body cavity, in particular for the treatment of trimethylaminuria or of bacterial vaginosis and the prevention of cardiovascular diseases
作者： Corinne Malpuech-Brugere , Jean-François Brugere , Guillaume Borrel , Paul William O'toole , Monique Alric
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摘要: Composition containing a microorganism, preferably an Archaea, expressing TMA methyltransferase and methyl group acceptor corrinoid protein, capable of metabolizing trimethylamine (TMA) in the presence hydrogen human cavity, such as intestine or vagina, for use medicament treating, reducing eliminating at level cavity. In addition, composition protein. These compositions are treating trimethylaminuria, vaginal fluids case bacterial vaginosis odours due to TMA. also plasma TMAO, preventing formation atheroma plaques and/or cardiovascular diseases.
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