Using “Uterine Index” to diagnose embryonic death in mares

摘要: Abstract Embryonic death plays an important role in infertility mares, and most of embryonic mortality occurs at early stage (before day 40) pregnancy. Previous investigations focused on B-mode sonographic images to determine abnormal pregnancy; however, no study has provided a quantitative objective method diagnose death. Here we developed new index, “Uterine Index,” using color Doppler sonography describe alterations uterine blood flow physiological pathological gestations during gestation. Six Trotter mares were used this study. The pregnancies interrupted with prostaglandin F2α (PGF 2α ) analog (tiaprost) days 25, 30, 40. Three investigated each stage. After the PGF administration, these examined every 8 hours until vesicles not visible ultrasound. In control group, three daily from 12 60. embryo size was measured sonography, arteries resistance index (RI) (UI) calculated. RI values artery lower pregnant side compared that non-pregnant 15 on, difference became greater as pregnancy advanced ( P -treated UI reduced level approximately 0. As 32 before death, observed significant between treated mares. On contrary, different normal Through analysis all recorded values, suggest 10 5 are good for distinguishing (UI >10)