Bilateral renal cortical necrosis

摘要: Abstract Bilateral renal cortical necrosis is a pathological diagnosis of clinical entity characterized by the abrupt onset gross hematuria, oliguria and anuria, usually in individuals without known disease, proceeding to uremic syndrome with predominantly fatal outcome. Pathologically, there patchy diffuse bilateral ischemic coagulative necrosis, characteristic sparing medulla. Its greatest incidence pregnant women accidental hemorrhage (abruptio placentae) last trimester. It may also occur infants children, as result diarrhea dehydration, while men it occurs infections or poisons. main feature sudden anuria. The difficult but aided percutaneous needle biopsy. Experimentally, has been produced animals principally intravenous injection bacterial toxins vasoconstrictor substances. Although believed from spasm interlobular arteries afferent arterioles, its exact pathogenesis remains obscure. treatment similar that employed other causes acute insufficiency. Proper management makes survival possible.