Facially amphiphilic polymers and oligomers and uses thereof

作者: Gregory N. Tew , William F. Degrado , Sungwook Choi , Michael L. Klein , Jing Yuan

DOI:

关键词:

摘要: The present invention discloses methods of use facially amphiphilic polymers and oligomers, including pharmaceutical uses the oligomers as antimicrobial agents antidotes for hemorrhagic complications associated with heparin therapy. also novel their compositions, compositions. further design synthesis oligomers.

参考文章(238)
J Van Ryn-McKenna, L Cai, F A Ofosu, J Hirsh, M R Buchanan, Neutralization of enoxaparine-induced bleeding by protamine sulfate. Thrombosis and Haemostasis. ,vol. 63, pp. 271- 274 ,(1990) , 10.1055/S-0038-1645207
Richard B. Phillips, David M. Roush, Susan E. Eurkart, 2-Substituted ethynyl thiophene pesticides ,(1988)
Barbara F. Zimmerman, Allan E. Querens, Henry R. Rawls, Interpolymeric resin for treatment of teeth ,(1984)
J Harenberg, Pharmacology of low molecular weight heparins. Seminars in Thrombosis and Hemostasis. ,vol. 16, pp. 12- 18 ,(1990)
Gregory N. Tew, Subramani Iyer, Samuel I. Stupp, Julia J. Hwang, Harm Anton Klok, Li Sheng Li, Self-assembling biomaterials American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. ,vol. 39, pp. 166- 167 ,(1998)
J. Sangster, Octanol-Water Partition Coefficients: Fundamentals and Physical Chemistry European Journal of Medicinal Chemistry. ,vol. 11, pp. 842- ,(1997)
Masayuki Tooyama, Masaaki Seya, Process for producing amphipathic polymers ,(2002)
Jih Ru Hwu, Abdolmajid Azaripour, Hasan Mottaghian, Wen Nan Tseng, Chun Chieh Lin, Gholam H. Hakimelahi, Ali A. Moshfegh, Shwu-Chen Tsay, Phloroglucide derivatives and their pharmceutical use ,(1998)
William F. Degrado, Design of Peptides and Proteins Advances in Protein Chemistry. ,vol. 39, pp. 51- 124 ,(1988) , 10.1016/S0065-3233(08)60375-7