Hepatitis C and Liver Transplantation in the HIV Co-infected Patients

作者: Teresa Maria Antonini , Jean Charles Duclos-Vallée , Didier Samuel

DOI: 10.1007/978-1-4614-8438-7_5

关键词:

摘要: The introduction of antiretroviral therapies (cART) has improved the survival patients infected with human immunodeficiency virus (HIV). Because shared ways transmission, 30 % HIV-infected have hepatitis B (HBV) or C (HCV) co-infection; so, till date, liver disease is a major cause non-acquired syndrome (AIDS)-related deaths. Survival end-stage shorter than in non-HIV-infected patients. For this reason, transplantation (LT) must be evaluated after first episode decompensation. risk opportunistic LT low, while HCV recurrence central problem and affects post-transplant patients’ survival. Standard anti-HCV therapy pegylated interferon ribavirin resulted low response rate. This should change advent new drugs better antiviral activity. would allow viral control from time transplant will improve results HCV/HIV co-infected

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