Selection of Patients with Acute Pulmonary Embolism for Thrombolytic Therapy

作者: Michael Terrin , Samuel Z. Goldhaber , Bruce Thompson , The TIPE Inoestigators

DOI: 10.1378/CHEST.95.5.279S

关键词:

摘要: During a recent one-year period, 44 clinical centers in the United States saw 2,539 patients with diagnoses of pulmonary embolism as supported by high probability lung scans and/or positive angiograms. In developing proposals for trial Thrombolysis Pulmonary Embolism (TIPE), investigators reviewed patients’ medical charts contraindications to thrombolytic therapy. Overall, 1,345 (53.5%) surveyed TIPE would have been acceptable treatment therapy, proportion higher than generally anticipated. Risks major blood loss were most frequent therapy and found 838 (33.3%) patients. CNS contraindicate 453 (17.9%) bleeding into special compartments 76 (3.0%) is underdiagnosed settings, even more survey could benefit from appropriate diagnosis treatment. The question remains whether will Only randomized provide satisfactory answer.

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