Retinal tumor induced in the baboon by human adenovirus 12.

作者: N Mukai , S. Kalter , L. Cummins , V. Matthews , T Nishida

DOI: 10.1126/SCIENCE.7434012

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摘要: Three of 21 newborn baboons injected intraocularly with human adenovirus type 12 developed an intravitreal mass to 36 months later. Two the masses were indistinguishable from retinoblastoma, a retinal tumor that afflicts children. To our knowledge this is first time retinoblastoma-like has been induced experimentally by in nonhuman primate.

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