First description of PVL-positive methicillin-resistant Staphylococcus aureus (MRSA) in wild boar meat.

作者: Britta Kraushaar , Alexandra Fetsch

DOI: 10.1016/J.IJFOODMICRO.2014.06.018

关键词:

摘要: Staphylococcus aureus is an important food-borne pathogen due to the ability of enterotoxigenic strains produce staphylococcal enterotoxins (SEs) in food. Methicillin-resistant S. (MRSA) also for humans, causing severe and hard treat diseases hospitals community its multiresistance against antimicrobials. In particular, harbouring genes encoding Panton–Valentine leukocidin (PVL) toxin are concern from a public health perspective as they usually capable skin soft tissue infections (sSSTIs) occasionally necrotizing pneumonia which associated with high mortality. This first report on detection MRSA PVL wild boar meat. Among 28 isolated meat course national monitoring programme Germany, seven harboured PVL-encoding genes. Six isolates were identical according results spa-, MLST-, microarray- PFGE-typing. They could be assigned epidemic clone USA300. Epidemiological investigations revealed that people handling food most likely common source contamination these MRSA. These findings call again suitable hygienic measures at all processing steps production chain. The study underline along chain essential closely characterise total burden health.

参考文章(64)
M. Sekkat, M. J. M. Bonten, A. Troelstra, N. Carpaij, M. B. Ekkelenkamp, [Endocarditis due to meticillin-resistant Staphylococcus aureus originating from pigs]. Nederlands Tijdschrift voor Geneeskunde. ,vol. 150, pp. 2442- 2447 ,(2006)
M.J. Ellington, M. Ganner, M. Warner, E. Boakes, B.D. Cookson, R.L. Hill, A.M. Kearns, First international spread and dissemination of the virulent Queensland community-associated methicillin-resistant Staphylococcus aureus strain Clinical Microbiology and Infection. ,vol. 16, pp. 1009- 1012 ,(2010) , 10.1111/J.1469-0691.2009.02994.X
M. Spohr, J. Rau, A. Friedrich, G. Klittich, A. Fetsch, B. Guerra, J. A. Hammerl, B.-A. Tenhagen, Methicillin‐Resistant Staphylococcus aureus (MRSA) in Three Dairy Herds in Southwest Germany Zoonoses and Public Health. ,vol. 58, pp. 252- 261 ,(2011) , 10.1111/J.1863-2378.2010.01344.X
Matthew K. Thompson, Mary E. Keithly, Michael C. Goodman, Neal D. Hammer, Paul D. Cook, Kevin L. Jagessar, Joel Harp, Eric P. Skaar, Richard N. Armstrong, Structure and function of the genomically encoded fosfomycin resistance enzyme, FosB, from Staphylococcus aureus. Biochemistry. ,vol. 53, pp. 755- 765 ,(2014) , 10.1021/BI4015852
Christiane Cuny, Robin Köck, Wolfgang Witte, Livestock associated MRSA (LA-MRSA) and its relevance for humans in Germany. International Journal of Medical Microbiology. ,vol. 303, pp. 331- 337 ,(2013) , 10.1016/J.IJMM.2013.02.010
Bettina Stieber, Stefan Monecke, Elke Müller, Vico Baier, Geoffrey W. Coombs, Ralf Ehricht, Development and usage of protein microarrays for the quantitative measurement of Panton-Valentine leukocidin. Molecular and Cellular Probes. ,vol. 28, pp. 123- 132 ,(2014) , 10.1016/J.MCP.2013.11.003