Mechanistic Concepts in Androgen-dependence of Prostate Cancer
作者： Noah Craft , Charles L. Sawyers
关键词:
摘要: Androgen blockade is the mainstay of therapy in clinical management advanced prostate cancer. Recent progress on two fronts – development newer xenograft and transgenic models a greater understanding nuclear receptor signaling has provided new insight into mechanisms androgen-dependence This review centers concept that perturbations androgen are likely to occur early cancer play critical role progression end stage hormone-refractory disease.
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sci-hub.se 参考文章(51)
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