Dictyostelium discoideum : A Model System for Cell and Developmental Biology
作者： Sabateeshan Mathavarajah , Ana Flores , Robert J. Huber
DOI: 10.1002/CPET.15
关键词:
摘要: The social amoeba Dictyostelium discoideum has long served as a model system for studying fundamental processes in cell and developmental biology. This eukaryotic microbe is also recognized organism biomedical human disease research since the genome encodes homologs of genes linked to disease, such those cancer neurodegeneration. unique life cycle composed unicellular growth phase multicellular that induced by starvation. During its cycle, undergoes conserved cellular including, but not limited to, proliferation, phagocytosis, intercellular signaling, adhesion motility, chemotaxis, differentiation. history organism, resources available researchers community, diverse ways used contemporary lab are discussed. © 2017 John Wiley & Sons, Inc. Keywords: Dictyostelium discoideum; growth; development; model system; human disease; host-pathogen interactions; social evolution
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