作者: S. Morrissey , E. D. Kudryashov , K. A. Dawson , V. A. Buckin
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摘要: We have used a combination of optical spectroscopy, fluorescence, isothermal titration calorimetry, surfactant-selective electrode techniques, high-resolution ultrasonic velocity and density measurements to study the binding cationic surfactant dodecyltrimethylammonium bromide short fragments, 200 base pairs, DNA in dilute solutions at 1 mM NaCl concentration. At first stage forms small aggregates on surface. This is accompanied by significant change secondary structure. second stage, we observed formation large