Induced theta oscillations mediate large‐scale synchrony with mediotemporal areas during recollection in humans

摘要: One functional aspect of theta oscillations that recent studies have begun to explore in humans is their role for the recollection personal events. A specific but not stimulus-familiarity would support links between cortical and hippocampal functioning, given hippocampus seems be more critical than stimulus-familiarity. During recollection, might mediate a dynamic link neocortical areas, thereby allowing recruit bind distributed representations. We recorded using whole-head magnetoencephalography while nine healthy subjects made recognition memory judgments on previously studied unstudied pictures faces. For each recognized face, indicated whether they also recollected background image front which face was studied. Theta were higher amplitude during absence accurate background. These induced nature, meaning showed considerable phase variability from trial trial. To nevertheless extract field distribution coherent single trials, we calculated differences sensor pairs at time point This information used localize brain sources synchronized theta-generators. The results suggest associated with activity increase synchronous network, including prefrontal, mediotemporal, visual areas. findings are compatible notion related binding representations recollection. © 2005 Wiley-Liss, Inc.