Chemical and Nervous Control of the Coronary System

摘要: Publisher Summary This chapter discusses chemical and nervous controls of the coronary system. Coronary blood flow is determined by perfusion pressure vascular resistance. However, supplied intermittently to myocardium, because noticeably reduced contraction muscular mass surrounding channels. The effects extravascular compression also affect pattern flow. curve decreases during systole, highest values are attained diastole when myocardium relaxes. At beginning isometric contraction, there a sudden fall in left ventricle extent that backflow sometimes occurs. systole generally moderate forward vessels, which increases quickly as aortic rises drops late systole. intravenous injection noradrenaline stimulation β-receptors, with isoproterenol or other adrenergic amines, elicit marked increase flow, mainly β 1 sympathetic myocardial, mechanical, metabolic activity lesser direct vasodilation excitation 2 -receptors. mediated local factors, either present produced myocardial activity, main regulator oxygen supply heart.