Serum antibodies to Toxoplasma gondii and Herpesvidae family viruses in individuals with schizophrenia and bipolar disorder: a case-control study.

摘要: BACKGROUND Recent etiological studies for schizophrenia and bipolar disorder have focused on the protozoan Toxoplasma gondii Herpesvirdae family viruses. OBJECTIVE To determine magnitude of T. gondii, cytomegalovirus (CMV), herpes simplex virus type 1 (HSV-1) 2 (HSV-2) infection in individuals with schizophrenia, healthy controls by using serologic diagnostic methods. MATERIAL AND METHODS Serologic method was used to prevalence level antibodies T CMV HSV-1 HSV-2 disorder, unaffected recruited from Butajira, Ethiopia. The study conducted March May 2009. A total 495 serum samples were analysed presence immunoglobulin G (IgG) HSV-1, HSV-2. RESULTS seroprevalence higher [adjusted odds ratio = 4.7; 95% CI (1.5, 15.1)] 3.0; (1.1, 8.6)] than controls. IgG also significantly bipoar Younger (< 25 years old) had a matched CONCLUSION This provides additional evidence that 7T may be associated some cases disorder. Additional should focus these agents sera CSF recent-onset psychosis.