Is administration of preoperative angiotensin-converting enzyme inhibitors important for renal protection after cardiac surgery?

摘要: Objective: There are various reasons for renal dysfunction after cardiac surgery; however, activation of the renin–angiotensin system has an important role following surgery. We investigated effect preoperative angiotensin-converting enzyme (ACE) inhibitors on functions cardiovascular Material–methods: Three hundred sixty-six patients awaiting elective surgery were allocated to two groups, namely treatment group, comprising ACE inhibitor group (n = 186), and control which was without 180). The parameters [blood urea nitrogen, creatinine, creatinine clearance, glomerular filtration rate (GFR)] need dialysis evaluated associated with between groups in postoperative period. Results: After surgery, requiring developed 11 (3.8%) patients. no required (p < 0.05). As an...