Hypoglycemia After Gastric Bypass: The Dark Side of GLP-1

作者: Mary-Elizabeth Patti , Allison B. Goldfine

DOI: 10.1053/J.GASTRO.2014.01.038

关键词:

摘要: … challenging and sometimes severe complication of roux-en-Y gastric bypass surgery is postprandial hyperinsulinemic hypoglycemia… -bypass hypoglycemia is GLP-1, a peptide released …

参考文章(28)
K. Müssig, H. Staiger, F. Machicao, H.-U. Häring, A. Fritsche, Genetic variants affecting incretin sensitivity and incretin secretion Diabetologia. ,vol. 53, pp. 2289- 2297 ,(2010) , 10.1007/S00125-010-1876-8
B. Laferrere, D. Reilly, S. Arias, N. Swerdlow, P. Gorroochurn, B. Bawa, M. Bose, J. Teixeira, R. D. Stevens, B. R. Wenner, J. R. Bain, M. J. Muehlbauer, A. Haqq, L. Lien, S. H. Shah, L. P. Svetkey, C. B. Newgard, Differential Metabolic Impact of Gastric Bypass Surgery Versus Dietary Intervention in Obese Diabetic Subjects Despite Identical Weight Loss Science Translational Medicine. ,vol. 3, ,(2011) , 10.1126/SCITRANSLMED.3002043
Carl Frederik Hansen, Marco Bueter, Nadine Theis, Thomas Lutz, Sarah Paulsen, Louise S. Dalbøge, Niels Vrang, Jacob Jelsing, Hypertrophy Dependent Doubling of L-Cells in Roux-en-Y Gastric Bypass Operated Rats PLoS ONE. ,vol. 8, pp. e65696- ,(2013) , 10.1371/JOURNAL.PONE.0065696
M. E. Patti, G. McMahon, E. C. Mun, A. Bitton, J. J. Holst, J. Goldsmith, D. W. Hanto, M. Callery, R. Arky, V. Nose, S. Bonner-Weir, A. B. Goldfine, Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia Diabetologia. ,vol. 48, pp. 2236- 2240 ,(2005) , 10.1007/S00125-005-1933-X
Marzieh Salehi, Amalia Gastaldelli, David A. D'Alessio, Blockade of glucagon-like peptide 1 receptor corrects postprandial hypoglycemia after gastric bypass. Gastroenterology. ,vol. 146, pp. 669- 680 ,(2014) , 10.1053/J.GASTRO.2013.11.044
A. B. Goldfine, E. C. Mun, E. Devine, R. Bernier, M. Baz-Hecht, D. B. Jones, B. E. Schneider, J. J. Holst, M. E. Patti, Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal. The Journal of Clinical Endocrinology and Metabolism. ,vol. 92, pp. 4678- 4685 ,(2007) , 10.1210/JC.2007-0918
Leao Zagury, Rodrigo O. Moreira, Erika P. Guedes, Walmir F. Coutinho, Jose C. Appolinario, Insulinoma misdiagnosed as dumping syndrome after bariatric surgery. Obesity Surgery. ,vol. 14, pp. 120- 123 ,(2004) , 10.1381/096089204772787419
J. C. Reubi, A. Perren, R. Rehmann, B. Waser, E. Christ, M. Callery, A. B. Goldfine, M. E. Patti, Glucagon-like peptide-1 (GLP-1) receptors are not overexpressed in pancreatic islets from patients with severe hyperinsulinaemic hypoglycaemia following gastric bypass. Diabetologia. ,vol. 53, pp. 2641- 2645 ,(2010) , 10.1007/S00125-010-1901-Y