摘要: The human major histocompatibility complex (MHC) was discovered during studies initiated by J. Dausset, R. Payne and van Rood describing a genetically inherited system of alloantigens [1–3]. Initially research generated little interest among biologists, primarily because the artificial nature underlying phenomenon, that is, rejection organ transplants. Later, however, MHC attracted great deal attention, this as result immunological research, which demonstrated molecules restrict specificity antigen receptor expressed on surface T lymphocytes, thus play role in regulation immune response [4].
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