Increasing incidence of thyroid cancer in the Commonwealth of Pennsylvania.

摘要: Importance The incidence of thyroid cancer in the United States has increased rapidly and Pennsylvania is state with highest rate country, although factors driving this increase are unknown. Moreover, it remains unclear whether represents a true disease or result overdiagnosis. Objective To compare tumor characteristics rest gain insight into influencing cancer. Design, Setting, Participants In population-based study, data on from Surveillance Epidemiology End Results 9 (SEER-9) registry Cancer Registry (PCR) 1985 through 2009 were collected reviewed for information regarding sex, race, histologic type cancer, staging, size at diagnosis. International Classification Diseases Oncology, Third Edition code C739 (thyroid carcinoma) was used to identify 110 615 records SEER-9 29 030 PCR. Main Outcomes Measures Average annual percent change (AAPC) across various demographic groups Pennsylvania. AAPC 7.1% per year (95% CI, 6.3%-7.9%) vs 4.2% 3.7%-4.7%) remainder States, trends significantly different ( P  = .60; but despite similarity between 2 groups, joinpoint models fit not parallel [ Conclusions Relevance rising faster than nation, as tumors that larger higher stage These findings suggest burden contributed Etiologic promoting rise must be investigated may provide drivers national